Clinical studies show that moderate doses of semaglutide are effective for weight management at 3 and 6 months when combined with lifestyle modifications such as a healthy diet, meal tracking, portion control advice, psychosocial support, and physical activity coaching
In a phase 2 trial of 338 adults with obesity, retatrutide given once weekly caused dose-dependent weight loss over 48 weeks
Tirzepatide, on the other hand, is a newer medication that combines the actions of GLP-1 with glucose-dependent insulinotropic polypeptide (GIP) receptor agonists
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The starting dose is not designed to suppress appetite
Here are some frequently asked questions about the drugs side effects and their answers