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Additionally, it is essential to embryonic development because it involves cell division, DNA synthesis, cellular differentiation, and the maintenance of cytoplasmic integrity

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Davioud-Charvet E, Delarue S, Biot C, Schwobel B, Boehme CC, Mussigbrodt A, Maes L, Sergheraert C, Grellier P, Schirmer RH and Becker K

In a different study, hepatic FOXO1 ablation in mice was compared with the simultaneous knockout of FOXO1 and FOXO3 and the triple ablation of the three isoforms, FOXO1, FOXO3, and FOXO4 in the liver