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Quantification of inflammatory and degradation marker Total mouse PGE 2 , IL-6, MMP-3, and MMP-13 concentration of primary murine chondrocytes (p0) or murine macrophage cell line (p + 9) after 24 h of treatment was assayed in cell-free supernatants using an ELISA kit, according to the manufacturers instructions

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Hypernatremia (due to the sodium content of valproic acid) or hyponatremia (due to valproic acid induced SIADH)

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