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This dosage range has been shown to be effective in clinical studies and sits well within the established safety margins
10.1038/416552a 77
In GPX5-gene KO mice, sperm DNA damage is significantly increased, while an 8-weeks pretreatment of GPX5 KO mice using antioxidants completely protects sperm DNA from oxidative stress damage ( 2.6 GPX6 Glutathione peroxidase 6 (GPX6), also known as olfactory organ glutathione peroxidase ( It is believed that GPX6 is mainly expressed in embryonic and olfactory organ epithelial cells, and may be involved in the transmission and degradation of odor-related signals
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Sucrose preference test For clarity and adherence to the experimental timeline, the sucrose preference test was performed after these behavioral tests to assess the impact of PCPA-induced insomnia on sucrose preference in the animals
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