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In people who develop hyperglycemia on statinsor who begin with pre-diabetesconsider therapies that enhance GLP-1 signaling (GLP-1 receptor agonists, DPP-4 inhibitors) or improve insulin sensitivity (metformin) while continuing evidence-based lipid lowering

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To maximize results, choose liposomal versions of both to ensure they survive the digestive process

Individuals with insulin resistance, type 2 diabetes, or previous weight loss plateaus may also benefit

The added glucagon activity appears to boost metabolic rate and fat burning, which likely explains the greater weight loss seen in trials

According to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), hypothyroidism affects approximately 5% of the US population (including both overt and subclinical cases), with higher prevalence among women and older adults