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The study was small and had short follow-up only averaging only 92 days, and patients in the PRP group reported a greater improvement (71%) compared to the needle fenestration group (79%) although this difference didnt reach statistical significance

When these collagen rich parts are subjected to heat, the long collagen molecules unwind and break down into smaller more soluble proteins, known as gelatin (1)

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Taken together, these results strongly suggest that ZIL possesses higher biocompatibility than DMSO and has great potential for application in the life sciences