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First, gene-expression changes in cultured cells exposed to a compound do not, by themselves, establish a systemic therapeutic effect in a living organism, let alone in a human

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A systematic review and meta-analysis of 37 randomized controlled trials found that levocarnitine supplementation produced modest but statistically significant reductions in body weight, BMI, and fat mass, particularly among adults with overweight or obesity

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The rationale involves addressing multiple aspects of aging simultaneously through cellular protection via telomerase and metabolic support via growth hormone optimization

[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Sikiric P., Marovic A., Matoz W., Anic T., Buljat G., Mikus D., Stancic-Rokotov D., Separovic J., Seiwerth S., Grabarevic Z., et al