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This effect might be explained that targeted nanocarriers help the internalization of ibuprofen and its anti-inflammatory action in brain endothelial cells

Duodenocutaneous fistula in rats as a model for wound healing-therapy in ulcer healing: the effect of pentadecapeptide BPC 157, L-nitro-arginine methyl ester and L-arginine

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Caffeine demethylation is assisted by two of the cytochrome P450 isoenzymes, CYP1A2 and CYP2C9 [20]