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It also exists in a soluble form (sKlotho) which is generated by cleavage of the extracellular domain of -Klotho, which circulates in the blood and also exerts systemic effects, including cardioprotective properties, which are still poorly understood [80, 82]

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The capsule shell is also made of HPMC, a gelatine-free capsule material based on vegetable cellulose

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Influence of caffeine on frequency of hypoglycemia detected by continuous interstitial glucose monitoring system in patients with long-standing type 1 diabetes