HDAC8 inhibition blocks SMC3 deacetylation and delays cell cycle progression without affecting cohesin-dependent transcription in MCF7 Cancer cells
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They possess antioxidant and anti-inflammatory properties in multiple diseases [198-200]
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Upon endocytosis, VacA disrupts intracellular calcium homeostasis, triggering the unfolded protein response (UPR) and endoplasmic reticulum (ER) dysfunction, which could even lead to mitochondrial dysfunction and cell death ( 3.2.2 Promoting macrophage polarization Macrophage phenotypes induced by H
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