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For the natural components with therapeutic effects, it is believed that future studies need to study deeply, and to improve the delivery route by combining nanotechnology and other methods to exert the best drug effect

It is also worth noting that, consistent with other incretin-based and glucagon co-agonist therapies, small mean increases in heart rate were observed in the trial

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[9,18] Although pharmacologic approaches are the most important treatment strategies for MDD, response rates to the first-line antidepressants are moderate and remission is observed in about 3045% of patients

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