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Payment Adjustment The current payment adjustment for a 5-year period from the implementation date of a new NTIOL class is $50 per lens

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[1] [4] Published phase 2 trial data (Jastreboff et al., NEJM , 2023) reported dose ranges from 1 mg up to 12 mg weekly, with higher doses associated with greater weight loss but also increased rates of gastrointestinal side effects

The following recommendations synthesize clinical trial protocols with practical considerations for Canadian users

doi: 10.1016/j.bjps.2009.10.027

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