Challenge Different types of nanoparticles have been employed as drug carriers to cross the BBB for treating CNS disease, resulting in notable progress
Monitoring gasdermin pore formation in vitro
Yang, Q
In a diabetic nephropathy mouse model overexpressing the receptor for advanced glycation end products (RAGE) and an AGE-induced endothelial-macrophage co-culture injury model, catalpol regulates the RAGE/Ras homolog gene family member A (RhoA)/Rho-associated kinase (ROCK) signaling pathway, interferes with the interaction between macrophages and endothelial cells, reduces endothelial injury and chemokine secretion, inhibits macrophage migration, and restores the M1/M2 phenotypic balance, improving the pathological damage in diabetic nephropathy (Shu, 2021
His diagnosis of lymphocytic colitis led to 10 years of frequent diarrhea and abdominal pain, treated only symptomatically
For a 50 mg vial, add 3 mL of bacteriostatic water