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These encompass a spectrum of maladies including malaise, fatigue and lethargy, appetite disturbances, non-cholestatic pruritus, muscle cramps, sleep disturbances, mental health disorders, gastrointestinal symptoms, sexual dysfunction, pain and peripheral neurological symptoms, hair loss and self-consciousness inducing skin changes

While effective, they require needles, refrigeration, and self-injection, which can be inconvenient or uncomfortable for some patients

Peer review Peer review information Nature Reviews Urology thanks the anonymous reviewers for their contribution to the peer review of this work

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1000 MG

Reconstituting three separate lyophilized vials introduces three opportunities for weighing error, contamination, and inconsistent concentration