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Several medications are also approved for pediatric obesity, including liraglutide, semaglutide, tirzepatide, and phentermine-topiramate in adolescents 12 years, whereas setmelanotide is restricted to specific genetically confirmed monogenic or syndromic obesity disorders in patients as young as 2 years depending on the indication

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Li C, Ostermann T, Hardt M, Ldtke R, Broecker-Preuss M, Dobos G, Michalsen A: Metabolic and psychological response to 7-day fasting in obese patients with and without metabolic syndrome