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Collectively, the data from 20 healthy nonobese subjects indicated that elevated colonic propionate production diminished striatal blood oxygen level-dependent signals, especially in reaction to high-energy foods, indicating that propionate mitigates reward-driven eating behavior through striatal pathways, irrespective of alterations in plasma PYY, GLP-1, glucose, or insulin levels

Am J Physiol Gastrointest Liver Physiol (2012) 303(7):G77585.10.1152/ajpgi.00155.2012 152 KawamataYFujiiRHosoyaMHaradaMYoshidaHMiwaMet alA G protein-coupled receptor responsive to bile acids

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[20] Researchers sought to validate earlier laboratory studies relating to carnitines effects on improving thyroid hormone levels