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71 (13), 45064517 (2011) O.R

Preclinical efficacy of the novel Monocarboxylate Transporter 1 Inhibitor BAY-8002 and Associated Markers of Resistance

Usually, patients with OC exhibit non-specific symptoms such as abdominal distension, pain, appetite loss, or increased frequency of urination during early development

*RI: Reference intake for an average adult ( 8400 KJ / 2000 kcal )

For example, starvation induces lysosomal Ca 2+ release through the TRPML1 channel, which activates TFEB by calcineurin and promotes autophagy (Medina et al., 2015)