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This makes it the first triple hormone receptor agonist with published clinical data in humans

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68 Detailed analysis suggests a multipronged effect of the changes in intestinal claudin-1 expression, including mucosal barrier properties (mucin-2 expression) and epithelial homeostasis

doi: 10.1016/j.neurobiolaging.2014.03.040

Its inclusion at low therapeutic doses contributes to the formula's overall electrolyte balance and complements the action of magnesium, with which it works in a tightly regulated physiological partnership