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Try putting something on television or using the cough trick let out a cough just before the needle pierces your skin to momentarily distract yourself

If you experience unexpected side effects or injection site reactions, seek advice from a healthcare professional promptly

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Meet our doctors Last reviewed: 16 Apr 2026 Sources Effectiveness of Low Doses of Semaglutide on Weight Loss and Body Composition Among Women in Their Menopause, Metabolic Syndrome and Related Disorders [accessed 10 April 2026] GLP-1 medicines for weight loss and diabetes: what you need to know, GOV.UK [accessed 10 April 2026] Semaglutide: Indications and dose, National Institute for Health and Care Excellence (NICE) [accessed 10 April 2026] Treatment - Obesity, NHS [accessed 10 April 2026] Wegovy 0.25 mg, FlexTouch solution for injection in pre-filled pen (PIL), emc [accessed 10 April 2026]

Semaglutide Risks: Primarily gastrointestinal