Court data shows thousands of cases overall focused primarily on GI injuries (e.g., gastroparesis in ~75% of sampled claims) and vision loss (at least 110 plaintiffs), with thyroid concerns tied to a boxed warning from rodent studies
[DOI] [PubMed] [Google Scholar] Wheeler MB, Lu M, Dillon JS, Leng XH, Chen C, Boyd AE., 3rd Functional expression of the rat glucagon-like peptide-I receptor, evidence for coupling to both adenylyl cyclase and phospholipase-C
These drugs were originally developed to treat patients with Type 2 diabetes as they produce insulin and lower blood sugar
A core highlight includes the Phase 3 ACHIEVE trial results for Foundayo, an oral small-molecule GLP-1 receptor agonist taken without food or water restrictions
Why GLP-1 drugs may affect your mood The answer appears to be a mix of biology, behavior and the reality of adjusting to a different relationship with food
Cell Death Differ 23 , 369379 (2016)