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[ref] Histamine is produced by the body at a basal level throughout the day and night
Researchers have investigated its potential effects on follicle cycling and scalp tissue health, areas where copper-dependent enzymatic activity is known to play a regulatory role
Of note, the possible contribution of the particular counteracting effect on the intravenous dextran- or egg whiteinduced anaphylactoid reaction (Duplancic et al., 2014) should also be considered, although not specifically mentioned in this review
Li Y,Sun B,Ma P
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it's addressing the underlying cellular imbalances that contribute to acne
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