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Globally, many in vitro and animal-based studies have demonstrated such preventive anticancer activity in colon, cervical, prostate, breast and lungs [50,64,65,66,67,68,69]

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162,163 Some trials have reported elevated pancreatic enzyme levels, 50,53 and further clarification is needed as to whether this indicates low-grade pancreatic inflammation

The fermentative properties of prebiotics can promote the proliferation of specific beneficial bacteria, leading to the production of metabolites such as butyrate

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Pancreatic polypeptide: a unique model for vagal control of endocrine systems