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It is also important to distinguish lactylation dependencies between resident microglia and recruited macrophages, and to integrate lactylation with glioma genotype and chromatin background, including IDH status, to identify truly lactylation-addicted tumors

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At the same time, markers of oxidative stress often increase

In addition, CYP24A1 showed significantly lower mRNA and protein expression levels in the liver of mice supplemented with VD+LC in comparison with VD-alone mice