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References Below are the direct links to the studies, articles, and resources mentioned throughout this article

10.1093/hmg/ddt516 36 XuY.GongB.YangY.AwasthiY

10.1186/1742-2094-9-52 J

The CLOCK/BMAL1 heterodimer combines with the E-box response element which located in the promoter region to stimulate the expression of other target genes, the core of which is the transcriptional expression of other clock genes, such as Periods ( PER1 , PER2 , and PER3 ), and Cryptochromes ( CRY1 and CRY2 )

Aging (Albany NY) 2013