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Additionally, investigations into NAD+'s role in hypertension models have indicated effects on blood pressure regulation and vascular function in research animals

Over a 10-year period, the prevalence in younger individuals increased by 36% , from 4.5% to 7.8%, significantly outpacing the 11% rise in older individuals (ages 40 and above)

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Sci Sports 34(2):6372 Parkhouse W, McKenzie D (1984) Possible contribution of skeletal muscle buffers to enhanced anaerobic performance: a brief review