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(2019) 27:256778.e6

According to Honigber and colleagues, semaglutide and dulaglutide received the same indication in 2020

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Indeed, oxidized Hb binds to the cytoplasmic domain of band 3 protein in the RBC membrane (Figure 2), triggering band 3 clustering, marking the erythrocyte for removal by splenic macrophages [23, 25]

Like any medication, it does have potential side effects, the most common being gastrointestinal (GI) issues Long-term studies are ongoing, but the benefits of significant weight loss, such as reduced cardiovascular risk and improved metabolic health, often outweigh these risks for many patients, says Dr