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Both of which regulate mitochondrial biogenesis and shift substrate utilization from glucose toward fatty acid oxidation
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10.1016/j.cmet.2019.09.009 56
Combination incretinamylin strategies: Trials combining Cagrilintide with GLP1 analogues (e.g., semaglutide, in CagriSema constructs) demonstrate synergistic weight loss and improved glycemic control compared to either agent alone
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Larger GST-fusion proteins sterically block each other from binding to proximal glutathione ligands
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