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10.3892/ol.2017.6053 259 WangK.TanS.-L.LuQ.XuR.CaoJ.WuS.-Q.et al (2018a)
Acetylation: NATs catalyze a ping-pong bi-bi mechanism: acetyl-CoA first acetylates a cysteine residue (Cys68) in the NAT active site, releasing CoA, and then the acetyl group is transferred from Cys68 to the substrate amine
Der schleichende Verlauf ist der geringen Geschwindigkeit der Stoffwechselprozesse geschuldet: Paracetamol wird in der Leber hauptschlich ber die Konjugation mit Glucuronsure und Schwefelsure metabolisiert und ber den Harn ausgeschieden
Bioengineered 12 (2), 1092410934
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