Ongoing research and investigational therapies, such as GIP/GLP-1/glucagon triple agonists, may inform future strategies for sustainable weight loss after discontinuation of weight loss pharmacotherapy
In 2021, it was approved as a once weekly injection for chronic weight management in adults and kids down to age 12 as Wegovy
A four-week escalation phase that seems slow initially often means better adherence and outcomes at month six
Despite the impressive results achieved, weight reduction is still considerably lower than bariatric surgery leaving important unmet medical needs and opportunities for obesity treatments
On safety, the published Phase 2 data reported that gastrointestinal effects nausea, vomiting, and constipation among them were the most common adverse events, were generally mild to moderate, and usually occurred during the escalation phase of the protocol
A 2016 study offered another intriguing possibility that targeting the molecular pathways that govern hair pigment could restore hair color