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[14] Small clinical trials indicate that maternal supplementation of 4,000 IU day or staggered 50,000 IU oral doses can safely maintain 25-hydroxyvitamin D above 30 ng mL without inducing hypercalcaemia, whereas single injections of 300,000 IU are reserved for severe malabsorption emergencies when benefits outweigh theoretical teratogenic risk

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How long you feel the effects can depend on your starting levels, which is why people with a larger deficiency sometimes notice the benefits over a longer stretch