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OA returned after 4-, 8-, and 12-weeks to measure liver transaminases and creatinine, assess adherence, and replenish supplements

Duan D, Moeckly C, Gysbers J, Novak C, Prochnow G, Siebenaler K, et al

Patients with inflammation of the joint are often excluded from cartilage repair attempts given that catabolic cytokines and proteinases (MMPs) present in the synovial fluid degrade the native ECM, and would similarly degrade any implanted tissue, predisposing treatment failure

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Sermorelin is a Growth Hormone Releasing Hormone (GHRH) that stimulates directly binds to the pituitary gland to release growth hormone

Most injection-site reactions are minor and localized