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Mass spectrometry imaging (MSI): Matrix-assisted laser desorption/ionization (MALDI) MSI allows researchers to map glutathione distribution across tissue sections with spatial resolution on the order of tens of micrometers

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While phase I and phase II enzymes are majorly responsible for chemically modifying the hydrophobic toxin to make it more hydrophilic, phase III is mostly related to the function of drug efflux performed by those drug transporters, such as the multidrug resistance (MDR) pump

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Thats why you need to ask your vet to include a GGT test which will help you get to the bottom of the cause of your dogs high enzyme numbers

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