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As mentioned above, one of the ways that cells can enter senescence is when their telomeres are shortened beyond usefulness the cell may (or may not) still be working well, but it has lost the ability to divide

doi: 10.1038/s41598-021-82917-7 77 PhillipsDCWoollardKJGriffithsHR

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Preclinical research models have explored its interactions with angiogenic signaling, tissue response pathways, and receptor-associated biological mechanisms in small-animal and in-vitro studies

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