Neuron 100 , 330348 (2018)
5.4 Experimental validation of epigenetic mechanisms Recent technological advances in genome editing and single-cell analysis have provided powerful tools to validate EED-induced epigenetic modifications as causal mechanisms underlying transgenerational reproductive toxicity
The key master antioxidant, glutathione, serves as a guardian of skin integrity, a supporter of gastrointestinal well-being, and a potential reducer of oxidative stress
10.1038/s41591-019-0375-9 Nat
Principal Investigator on A Randomized, Double-blind, Multicentre, Parallel-group, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Aticaprant 10 mg as Adjunctive Therapy in Adult Participants with Major Depressive Disorder (MDD) with Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy. Principal Investigator on A Study of Disease Characteristics and Real-life Standard of Care Effectiveness in Patients with Major Depressive Disorder (MDD) With Anhedonia and Inadequate Response to Current Antidepressant Therapy Including an SSRI or SNR. (Janssen)
At the molecular level, this compound is studied for its potential influence on neurotransmitter-related signaling cascades, particularly those involving dopaminergic pathway modulation
