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Compelling evidence implicates the kynurenine pathway (KP), activated by inflammatory cytokines and stress-related signals, as a critical mediator connecting these factors

Functionally, SLC25A39 overexpression promoted LUAD cell proliferation and migration, while its knockdown or deletion suppressed these malignant traits in vitro and in vivo

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Among these, random mutagenesis techniques such as ultraviolet (UV) irradiation effectively generate phenotypic diversity without using recombinant DNA technology (Jeyachandran et al., 2024)

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