In one study, more than half the participants (54%) had no previous use of oral glucose-lowering medication [22], while in another study, all participants were on a stable dose of insulin glargine with (83%) or without (17%) metformin [19]
Whilst some laboratory studies and small-scale human trials have suggested that certain probiotic strains may influence gut hormone levels, there is currently no robust clinical evidence demonstrating that probiotic supplements can reliably increase GLP-1 production or lead to clinically significant weight loss in humans
Customer Amy Spencer pays only $50/month for a concoction that mimics the effect of brand Wegovy/Zepbound, compared to ~$500/month commercial cost ( [7] )
Second, we did not assess adherence to medication in the sample
Original research articles were included if they offered novel mechanistic insights or translational data on a qualifying compound
These studies are all Cardiovascular Outcomes Trials, which are large multi-country and multi-center RCTs
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