glp 1 disorders Experts express alarm that GLP-1 RAs may trigger or worsen eating disorders. But is there any role they might play in binge eating disorder? And how can clinicians protect patients from risk? A new Science Perspective highlights

Sulagna Dutta, orcid.org/0000-0002-7893-5282

Rather than using the full therapeutic dose thats prescribed for active weight loss or blood sugar control, micro-dosing involves using smaller, less frequent doses of GLP-1 medications to maintain the metabolic benefits

Therefore, we examined the genes with the greatest log-fold increase in response to liraglutide treatment in cells, which encode a secreted factor

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However, this effect has not been conclusively demonstrated in primates, and human thyroid C-cells express GLP-1 receptors at much lower levels than rodent C-cells