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It protects cells from reactive oxygen and nitrogen species

Your clinician remains available for ongoing support, dose adjustments, and side-effect management

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Evidence grade: mechanistically credible, clinically unproven

In people with obesity, IGF levels are raised, which may partly explain the increased risk of developing endocrine cancers, as well as further implicate IGF-1 in cancer development 47

Understanding these contributing mechanisms enables healthcare providers to implement targeted management strategies, optimize treatment tolerability, and distinguish medication-related fatigue from potentially serious underlying conditions requiring further evaluation