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doi: 10.1124/dmd.113.053082

Risk of more severe side effects : Although rare, theres a possibility of more serious side effects, including pancreatitis or changes in vision

These include direct inhibition of inflammasome components, caspase-1 blockade, modulation of immune responses using anti-inflammatory agents, and targeted manipulation of gut microbiota and bile acid metabolism, which are increasingly recognized for their roles in liver homeostasis and injury response