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Gq/11 interacts with PLC, which may split a fat-like molecule, phosphatidylinositol 4,5-bisphosphate (PIP2), into two messaging molecules: IP3 (Inositol trisphosphate) and DAG (Diacylglycerol)

Although it was approved in 1994, its still a first-choice treatment for diabetes, says Michelle Ponder, MD, an endocrinologist and assistant professor of medicine at Duke University

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Based on published research and laboratory observations, some individuals may notice appetite-related changes within approximately one week, while others may require two to four weeks before more consistent changes are observed