Hope is not a treatment plan
Antidepressants (particularly mirtazapine, paroxetine, and some tricyclics), antipsychotics, corticosteroids, certain blood pressure medications (like beta-blockers), and some antihistamines taken regularly can all work against weight loss
Li L, Gang X, Wang J, Gong X (2022) Role of melatonin in respiratory diseases (Review)
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It actually induced an almost 10% increase in lean mass!However, this is what you might call a proof of concept study and has not yet been approved for humans taking a GLP-1 drug