where does glp-1 come from and the kidney: physiology to pharmacology and outcomes in diabetes GLP-1 Drugs: Fighting Diabetes and

2025;26(1):e13841

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Introduction to GLP-1 Receptors Glucagon-like peptide-1 (GLP-1) is a crucial hormone in the glucagon family, primarily secreted by intestinal L-cells distributed along the gastrointestinal tract

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As for kidney diseases, autophagy may protect functions in both glomerular and tubular compartments by suppressing excessive inflammation and fibrosis in AKI, CKD, and DN (Plat et al., 2020) and activate the mTOR signaling to inhibit podocyte autophagy

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