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Description

Pifithrin- induces necroptosis through oxidative mitochondrial damage but accompanies epithelialmesenchymal transition-like phenomenon in malignant mesothelioma cells under lactic acidosis

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Keep a reusable water bottle within reach

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Elrick H, Stimmler L, Hlad CJ, Jr., Arai Y

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Full geometry optimizations, relaxed scans and transition structure searches were carried out with Gaussian 16 83 with the ONIOM 84 QM/MM method using the B3LYP hybrid functional 85 and 6-31 G(d) basis set with ultrafine integration grids for the QM part and the ff14SB 78 , gaff2 79 and TIP3P 86 force fields for the MM part (protein, substrate and water, respectively) with electrostatic embedding

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The continuous glucose monitoring system (CGMS) was applied (MiniMed

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