CADTH Reimbursement Review: semaglutide (Wegovy - Novo Nordisk Canada Inc.)
Pregnancy Planning: Because semaglutide takes approximately five weeks to clear, Novo Nordisk and the FDA recommend stopping Ozempic or Wegovy at least two months before attempting to conceive
Each of these 3 incretins have somewhat different effects, both at the gut level and via the brain, regarding reduced appetite, increased energy expenditure, nutrient storage and substrate utilization, insulin secretion, promotion of satiety, delay of gastric emptying, or reduced systemic inflammation
The dose increases after at least 4 weeks at 2.4 mg, if more weight loss is clinically needed
A qualified endocrinologist or primary care physician should evaluate your individual risk-benefit profile before initiating GLP-1 therapy
Most protein and peptide pharmaceuticals are immunogenic