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Metformin slows down aging and extends life span of female SHR mice

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doi: 10.1016/j.xjidi.2022.100116

doi: 10.1128/MCB.6.7.2731 233

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Rather than simply blocking these enzymes, copper peptides promote the synthesis of tissue inhibitors of metalloproteinases (TIMPs), creating a balanced environment where old, damaged collagen is removed while new, healthy collagen is produced