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Side effect profile and tolerance : Gastrointestinal adverse effectsparticularly nausea, vomiting, and reduced appetiteare the most common side effects of GLP-1 receptor agonists, especially during dose escalation

Metabolic engineering for high yielding L(-)-carnitine production in Escherichia coli

GLP-1 (glucagon-like peptide-1) is a hormone naturally produced in the gut that plays a key role in appetite regulation, insulin signalling and blood sugar balance

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Waist circumference fell more too

Combining other metabolic conditions, such as diabetes and obesity, with an imbalanced fat metabolismwhich is a pro-atherosclerotic factormay significantly increase the risk of cardiovascular disease (CVD), especially in people with CKD (145)