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In addition, palbociclib led to the upregulation of genes and proteins involved in lipid metabolism, including glycerophospholipid and triacylglycerol (TAG) biosynthesis, sphingolipid synthesis, arachidonic acid metabolism, and peroxisomal lipid metabolism correlating with the lipidomic findings (Supplemental Fig

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In: AggarwalBBSurhYJShishodiaS, editors