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A randomized, double-blind study of larazotide acetate to prevent the activation of celiac disease during gluten challenge
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No adverse effects were noted in clinical trials (ulcerative colitis, phase II) [84,85], and in toxicological studies, a lethal dose (LD1) was not achieved (for review, see [11,12,13,14,24,25])
Any of these indicates the vial should be discarded
After analyzing complete trial data from the New England Journal of Medicine and clinical experience managing 340+ patients on GLP-1 and GIP agonists, one pattern emerged: patients who understand the timeline and prepare for peak side effects succeed