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In addition, some researchers have used immunotherapy and synthetic biology to design living bacteria, combining immunotherapy expression with optimized lysis mechanism, so that living bacteria can carry nanobodies back to the core of necrotic tumors, grow to a critical density, and lyse, effectively and continuously releasing therapeutic drugs in the tumor microenvironment

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However, the most important evidence is consistent beneficial effect of BPC 157 also in those areas that were most affected ( Table 8, Fig