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Methods: Thirty-six rats were allocated to six groups, one control group and five MTX groups, where induction of hepatotoxicity was achieved via injecting MTX (20 mg/kg)
It's also commonly used to address conditions like Long COVID, autoimmune diseases, insulin resistance, and even fertility challenges
Declarations Authors contributions Wrote the manuscript: Nguyen TL, Durn RV Secured funding: Durn RV Availability of data and materials Not applicable
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487,488 Therefore, melatonin or novel analogues may be promising drug therapies for improving behavioural disorders in autism